Retinalganglioncells相关论文
视网膜神经节细胞（RGC）是视觉通路中最重要的一类神经细胞，其轴突组成的视神经是视觉信号传递到大脑的唯一通路，对RGC的形态学特性、基......
A network pharmacology-based strategy for predicting the protect-ive mechanism of Ginkgo biloba on d
Hallmarks of the pathophysiology of glaucoma are oxidative stress and apoptotic death of retinal ganglion cells(RGCs).Gi......
青光眼是由于病理性眼压升高引起视神经结构和功能损害而导致的不可逆性致盲眼病，具有多因性、强异质性的特点，长期以来降低并控制眼......
目的:探讨程序性坏死特异性抑制剂necrostatin-1(Nec-1)对急性高眼压大鼠模型中视网膜神经节细胞(RGCs)程序性坏死的抑制作用。方......
The effect of mesenchymal stem cells on retinal ganglion cell-5 and endoplasmic reticulum stress pat
Purpose Apoptosis of retinal ganglion cells(RGCs)is one of the common pathological features associated with optic nerve ......
Recent evidence suggests that,in addition to the glutamatergic bipolar cells,amacrine cells(ACs)which are normally thoug......
Activation of cannabinoid type Ⅱ receptors modulates T-type voltage-gated calcium channels in rat re
Endocannabinoid signaling is involved in regulating multiple neuronal functions in the central nervous system,by activat......
Crocin upregulates CX3CR1 expression via suppressing NF-kB/YY1 signaling and inhibits lipopolysaccha
Objective Glaucoma is a group of neurodegenerative diseases characterized by the progressive loss of retinal ganglion ce......
Role of Müller cell-specific reactive gliosis in acute ocular hypertension-induced retinal damage of
Objective To observe Müller cell-specific reactive gliosis in rat retina following acute ocular hypertension (AOH) and ......
Lycium barbarum polysaccharides delay the functional decay of retinal ganglion cells during photorec
Retinitis pigmentosa (RP) is a hereditary retinal disease with progressive loss of rods followed by cones that lead to b......
Activated microglia promote oxygen-glucose deprivation/reperfusion induced retinal ganglion cells ap
Purpose Retinal ischemia/reperfusion(I/R)injury causes the death of retinal ganglion cells(RGCs),however the underlying ......
Neuroprotective Effects of Papaverine on Retinal Ganglion Cells in a Rat Optic Nerve Transection Mod
Objective Elevation of intraocular cAMP facilitates neuronal survival in CNS.Papaverine is an panphosphodiesterase inhib......
Aims Optic nerve is composed of retinal ganglion cell(RGC)axons which flock together at the optic disc and across sclera......
Optic nerve injury induces retina ganglion cells (RGC) death and loss of visual function in mammals, but not in low vert......
Involvement of transcription initiation factor ⅡB in the light-induced death of rat retinal ganglion
Transcription initiation factor ⅡB (TFⅡB) is a general transcription initiation factor that plays a pivotal role in th......
The inability of retinal ganglion cells (RGCs) to regenerate their axons after optic nerve damage has dire consequences ......
Taurine protecting ganglion cells against glutamate-induced ezcitotozicity by stabilizing calcium ho
Taurine is known to act as an osmoregulator and an inhibitory neuromodulator in central nervous system．Recent researches ......
Objective to analyze the clinical application value of Photopic Negative Response(PhNR)in amblyopia by comparing the nor......
Minocycline protects retinal ganglion cells after optic nerve crush injury in mice by delaying autop
...
青光眼是一组以视网膜神经节细胞(RGCs)渐进性死亡及其轴突慢性退化为特征的神经退行性疾病，主要与病理性眼压升高有关。自噬，即细胞......
Characteristics of retinal ganglion cells’firing activities during response to high-order statistics
Visual stimulus statistics are the fundamental parameters to provide reference for studying visual coding rules.The ......
细胞焦亡是一种继细胞凋亡、细胞坏死及自噬之后新发现的炎性体介导的程序性促炎性反应造成细胞死亡方式，其主要信号通路包括依赖半......
Achyranthes bidentata polypeptides (ABPP) have been reported to inhibit apoptosis of retinal ganglion cells (RGCs).The p......
Neuroprotective effects of ClC-3 chloride channel in glutamate-induced retinal ganglion cell RGC-5 a
Transforming growth factor β plays a role in regulation of apoptosis in ClC-3 and the Smads signaling pathway, although......
A rabbit model of traumatic optic nerve injury, established by occlusion of the optic nerve using a vascular clamp, was ......
Dose-dependent and combined effects of N-methyl- D-aspartate receptor antagonist MK-801 and nitric o
This study investigated the effects of daily intraperitoneal injections of N-methyl-D-aspartate receptor antagonist MK-8......
Erythropoietin upregulates growth associated protein-43 expression and promotes retinal ganglion cel
In this study, we established a rat model of optic nerve crush to explore the effects of erythropoietin on retinal gangl......
Endoplasmic reticulum stress is closely involved in the early stage of diabetic retinopathy.In the present study,a strep......
Molecular mechanisms of the Kru?ppel-like family of transcription factors(KLFs)have been studied more in proliferating c......
Etomidate affects the anti-oxidant pathway to protect retinal ganglion cells after optic nerve trans
Our previous studies revealed that etomidate, a non-barbiturate intravenous anesthetic agent, has protective effects on ......
The pathogenesis of glaucoma is still not fully clarified but a growing body of evidence suggests that neuroinflammation......
Glaucoma,the leading cause of visual impairment and irreversible blindness worldwide,is a multifactorial,progressive opt......
目前,青光眼的发病机制仍未明确,眼压升高、缺血、神经营养因子的剥夺、胶质细胞的激活、谷氨酸兴奋性反应等多种机制均可以促进青......
Purpose: To study the densities and distribution of retinal ganglion cells(RGC) in adult rat retinae with flurogold(FG) ......
青光眼是一种由青光眼性视神经病变引起视野缺损并最终致盲的眼病.青光眼性视神经损伤主要表现为视网膜神经节细胞(RGCs)的死亡,其......
青光眼是一种视网膜视神经的退行性病变,以视网膜神经节细胞(RGCs)的凋亡为基本病理基础,但其凋亡的具体机制尚未完全阐明.目前,大......
Neuroprotective effect of Qinggan Lishui formula on retinal ganglion cell apoptosis in a microbead-i
OBJECTIVE:To investigate a possible mechanism for protective effects of a decoction of the Qinggan Lishui formula (QF) o......
青光眼是全球主要的致盲眼病之一,以最终导致视网膜神经节细胞(RGCs)逐渐凋亡及其轴突丢失为主要特征.目前,降低眼压是控制青光眼......
线粒体动力学是指细胞中的线粒体不断地分裂、融合、移动、运输和线粒体自噬等,这些动态的过程在调节线粒体的形态与功能中发挥关......
目的检测嘌呤受体P2X7信使RNA(mRNA)及其蛋白在RGC-5细胞系的表达。设计合成针对P2X7受体的小型干扰RNA(siRNA)，并筛选出其中能高效......
目的制作大鼠视神经横断损伤模型，在损伤视神经的同时保留视神经鞘，为视神经损伤后再生的研究提供模型基础。方法SD大鼠20只，随机分为......
目的研究法舒地尔(Fasudil)对大鼠视神经损伤后视网膜组织睫状神经营养因子(CNTF)表达的影响，探讨法舒地尔对视网膜神经节细胞(RGCs......
目的研究银杏叶提取物EGb761对大鼠视神经夹伤后视网膜神经节细胞凋亡的保护作用。方法将40只Wistar大鼠随机分为实验组和对照组，每......
目的探讨法舒地尔(Fasudil)对大鼠视神经损伤的修复作用。方法将60只SD大鼠随机分成3组：正常组12只、对照组(生理盐水组)、治疗组(......
Effects of minocycline on apoptosis and neuronal changes in retinal ganglion cells from experimental
BACKGROUND: Minocycline, a tetracycline derivative, is neuroprotective in models of various neurological diseases.OBJECT......
目的 探讨重组腺伴随病毒载体介导的脑源性神经营养因子(rAAV-BDNF)对体外培养的鼠视网膜神经节细胞(RGCs)转染及其生长活性的影响......
Induction of Heat Shock Protein 72 in RGCs of Rat Acute Glaucoma Model after Heat Stress or Zinc Adm
Purpose :To investigate the dynamics of heat shock protein 72 (HSP72) expression in retinal ganglion cells (RGCs) in rat......
